Jayden Short will miss Saturday's clash with the Western Bulldogs, while Dustin Martin and Jacob Hopper are set to return.
Short has been ruled out of the Round 4 match at the MCG due to the calf issue which also saw him unavailable for Round 3.
SCROLL DOWN FOR THE FULL INJURY LIST >>>
Martin and Hopper both also missed last Friday night's game against Collingwood through general soreness and a knee complaint respectively.
"Jayden will progress through a gradual running program and is unavailable in the short-term," Physical Performance Manager Luke Meehan said.
"We're putting in some strong rehab training to make sure that we get it right for the rest of the season.
"Dustin and Jacob trained strongly over the weekend and are available to play."
Young defender Tom Brown will be unavailable for the medium-term after suffering a setback in his recovery from a wrist injury.
"Unfortunately Tom had an appointment with a specialist on Monday and the decision has been made to have surgery on his wrist, ruling him out for the medium-term," Meehan said.
