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Scans have revealed Richmond midfielder Jacob Hopper suffered a left soleus strain during last Friday night's 24-point win over Geelong at the MCG.
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The 26-year-old, who was subbed out in the third quarter against the Cats, will be unavailable for the medium-term.
Meanwhile, co-captain Toby Nankervis (ankle) is a chance to return for this Saturday night's Dreamtime at the 'G clash, as is young defender Tylar Young (leg).
Richmond Injury List:
Test
Tylar Young, leg
Toby Nankervis, ankle
Unavailable
Maurice Rioli, hamstring (short-term)
Tom Brown, wrist (short-term)
Jacob Hopper, soleus (medium-term)
Ivan Soldo, foot (medium-term)
Seth Campbell, adductor (medium-term)
Josh Gibcus, hamstring (medium-term)
Kaleb Smith, ankle (long-term)
Tom Lynch, foot (long-term)
Robbie Tarrant, hip (indefinite)
Mate Colina, back (indefinite)